Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)-
squalamine
CAS: 148717-90-2
Molecular Formula: C34H65N3O5S
Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)- - Names and Identifiers
Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)- - Physico-chemical Properties
| Molecular Formula | C34H65N3O5S |
| Molar Mass | 627.96 |
| Density | 1.13±0.1 g/cm3(Predicted) |
| pKa | -3.49±0.18(Predicted) |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | Soluble in water. |
Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.592 ml | 7.962 ml | 15.925 ml |
| 5 mM | 0.318 ml | 1.592 ml | 3.185 ml |
| 10 mM | 0.159 ml | 0.796 ml | 1.592 ml |
| 5 mM | 0.032 ml | 0.159 ml | 0.318 ml |
Last Update：2024-01-02 23:10:35
Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)- - Reference Information
| biological activity | Squalamine(MSI-1256) is a compound with broad-spectrum antiviral activation. |
| Use | a broad-spectrum antimicrobial of aminosterols present in shark tissues. It is a novel indicator of steroids as host defense agents in vertebrates. |
| production method | Method 1: isolated from the stomach of a spiny horn shark and a sea-green horn shark. Method 2: Synthesis of 3-hydroxy -5-bile acid (3 beta-hydroxy-5-hydroxy acid), Chenodeoxycholic acid (Chenodeoxycholic acid), fucosterol (fucosterol 1), Dehydroepiandrosterone (Dehydroepiandrosterone) or vinyl alcohol ketone Acetate (pregnen alone Acetate) as a raw material to prepare. For example, the compound (I) can be obtained by a 12-step reaction using 3 β-hydroxy-5-cholic acid as a starting material, and the product is obtained by the following reaction. Hydrochloric acid acidification of Squalamine trihydrochloride. |
Last Update：2024-04-09 21:04:16
![Cholestane-7,24-diol,3-[[3-[(4-aminobutyl)amino]propyl]amino]-, 24-(hydrogen sulfate), (3b,5a,7a,24R)-](http://res.chembk.com/assets/str/2d/1/14/148717-90-2.png)
Supplier List
Product Name: squalamine Visit Supplier Webpage Request for quotation
CAS: 148717-90-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 148717-90-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: squalamine Visit Supplier Webpage Request for quotation
CAS: 148717-90-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 148717-90-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History